Lymphangioleiomyomatosis (or “LAM disease”) is a rare lung disease that primarily affects women of childbearing age (average age=35). The exact number of women with LAM is unknown but it is estimated that for every 1 million women in the world, 3-5 women will have LAM. This life-threatening disease is caused by slow accumulation of abnormal cells in the lungs. Normally, when we breathe in air, it flows through our breathing airways to the lungs, so that the lungs take up oxygen in the air to maintain body functions. However, in LAM disease, the abnormal cells block the breathing airways and damage the lungs, leading to difficulty in breathing. The most common symptoms of LAM include shortness of breath, chronic cough, unexplained tiredness, difficulty in breathing and chest pain.  There is currently no cure for LAM. However, an FDA approved drug known as “Sirolimus” has proven to improve lung function in some patients.